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Benjamin L. Prosser

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#gene editing Open access Sep 2026

Pathogenic KIF1A variants differentially disrupt axonal trafficking and impede synaptic development

Functional analysis of neuronal activity reveals delayed synaptic maturation in loss-of-function mutations and insights into how KIF1A mutations with distinct molecular-level impacts lead to significant downstream synaptic deficits in human neurons.

Jayne Aiken, Carris Borland, Nicolas Marotta et al. · 0 citations

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