Jul 2026
USP15-mediated deubiquitination of FIS1 impairs mitochondrial function and sensitizes bladder cancer cells to radiotherapy
USP15 plays a critical role in regulating radiosensitivity, and targeting USP15-mediated mitochondrial OXPHOS may represent a promising therapeutic strategy to enhance the efficacy of radiotherapy in bladder cancer, providing a novel treatment approach for the treatment of bladder cancer patients.
Ru-Xin Xiong, Ming-Xu Wang, Jiaming Du et al.
· Oncogene · 0 citations