Acute Stress Drives Adaptive Anxiety via Excitatory-Inhibitory Imbalance in the Prefrontal-Amygdala Circuit in Male Mice.
Using an acute restraint stress model in male mice, temporally restricted, projection-specific recruitment of dorsomedial prefrontal cortex (dmPFC) circuitry that regulates acute anxiety-like behavior is identified that attenuated ARS-induced anxiety-like behavior.