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Author

Bing-Xing Pan

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Jul 2026

Acute Stress Drives Adaptive Anxiety via Excitatory-Inhibitory Imbalance in the Prefrontal-Amygdala Circuit in Male Mice.

Using an acute restraint stress model in male mice, temporally restricted, projection-specific recruitment of dorsomedial prefrontal cortex (dmPFC) circuitry that regulates acute anxiety-like behavior is identified that attenuated ARS-induced anxiety-like behavior.

Jia-Xin Zou, En Cao, Zhi-Hao Wang et al. · 0 citations
Open access Sep 2026

ERK-dependent hyperexcitability of BLA neurons projecting to dCA3 underlies social dysfunction in a male mouse model of fragile X syndrome

A causal link from FMRP loss to circuit dysfunction and ERK pathway dysregulation is established, and it is suggested that targeting this pathway may offer a promising strategy for treating social dysfunction in ASD and FXS.

Si-Yu Wang, Xiao-Tong Wu, Si-Yuan Dong et al. · 1 citation

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