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Author

Brian M. Debo

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2 papers indexed here

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Open access Sep 2026

Thymic age and peripheral residence time determine antitumor competence of CD8+ T cells.

These findings establish developmental imprinting as an important determinant of CD8+ T cell heterogeneity and identify CXCR3+IL-18Rα+ CD8+ T cells as key effectors for antitumor immunity.

Yuan-Qin Yang, Yun-Yi Wang, Amanda Wicki et al. · 0 citations

CHROMATIN SEQUENCING Single-molecule regulatory architectures captured by chromatin fiber sequencing

Fiber-seq exposed widespread plasticity in the linear organization of individual chromatin fibers and illuminated principles guiding regulatory DNA actuation, the coordinated actuation of neighboring regulatory elements, single-molecule nucleosome positioning, and single-molecule transcription factor occupancy.

Andrew B. Stergachis, Brian M. Debo, E. Haugen et al. · 0 citations

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