Visualizing the Atomic-Level Impact of Anti-CRISPR II–C1 Inhibition on Geo Cas9 with Integrated Structural Biophysics
Abstract Anti-CRISPRs (Acrs) are small protein inhibitors of CRISPR-Cas effectors that originate from the translated genetic material of bacteriophage. Harnessing the natural ability of Acrs to bind and disrupt CRISPR-Cas editing can provide enhanced spatiotemporal control of gene editing. Recent studies have revealed...
Alexa L Knight, Helen B Belato, Praise Lasekan et al.
· JACS Au · 0 citations