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Oct 2026

A Biallelic ITGA10 Variant as a Candidate for Inherited Thrombocytopenia: Insights From a Whole-Exome Sequencing Cohort.

BACKGROUND Inherited platelet disorders (IPDs) are a heterogeneous group of diseases characterized by thrombocytopenia and/or platelet functional abnormalities. This study aimed to identify novel candidate genes associated with hereditary thrombocytopenia using whole-exome sequencing (WES). METHODS WES was performed...

D. Emecen, Tahir Atik, P. B. Kırmızıbayrak et al. · 0 citations
Sep 2026

Birinapant enhances cisplatin sensitivity in epithelial ovarian cancer through modulation of apoptotic and survival signaling pathways

The findings suggest that TNF-α responsiveness, cIAP1 (BIRC2)-related signaling, and the ability of cancer cells to activate apoptotic pathways, particularly caspase-8, may serve as potential biomarkers for identifying tumors more likely to respond to Birinapant-based combination therapies.

Elham Shahnazi, Arman Rostamlou, Aras Gezer et al. · 0 citations

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