Coronavirus diseases, particularly COVID-19, been associated with cardiac injury. Given that obesity is a well-known risk factor for severe cases with poorer outcomes, we hypothesized that cardiac involvement in a murine betacoronavirus infection would be exacerbated in pre-obese mice. To test this hypothesis, we fed m...
Aline Borges BarbosaTeles, Larisse de Souza Barbosa Lacerda, Rafael Ferreira Calil et al.· Cytokine· 0 citations
Investigation of the safety and therapeutic potential of (2E,5E)-2,5-bis(isoquinolin-5-ylmethylene)cyclopentanone (ICP) against Leishmania infantum indicates that it represents an interesting chemical scaffold for further optimization and investigation toward the development of new treatments for leishmaniasis.
Isabela Cristina Soares Martins, T. T. Santos, C. Queiroz-Junior et al.· Acta Tropica· 0 citations
Helicteres ovata extract exhibits significant antiallodynic effect in chemotherapy-induced neuropathic pain, mediated by inflammatory and neuromodulatory pathways and holds promise as a phytotherapeutic candidate for neuropathic pain management.
R. C. de Matos, A. F. A. Bitencourt, Pedro Augusto Lemos Santana et al.· Journal of Ethnopharmacology· 0 citations
Systemic delivery of M(IL4) attenuated MHV-A59-induced inflammatory responses, as evidenced by reduced pro-inflammatory cytokine levels, decreased lung tissue damage, and enhanced viral clearance and pave the way for further investigation of macrophages as therapy for individuals with severe cases of respiratory viral...
F. B. Felix, V. A. Beltrami, Ana Paula Soares da Cruz Maravilha et al.· International Immunopharmaco...· 0 citations
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