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Author

Can Wang

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Open access Oct 2026

Characterization of a K62-specific phage depolymerase and its protective effect in a mouse model of Klebsiella pneumoniae infection.

Multidrug-resistantKlebsiella pneumoniae has emerged as a formidable healthcare challenge, driving the urgent need for alternative therapeutic strategies such as phage therapy. In this study, we isolated and comprehensively characterized a novel phage, designated vB_Kp_IME328 (IME328), which exhibits highly specific ba...

Can Wang, Rui-Lin Yang, Jin-Pan Wei et al. · 0 citations
Aug 2026

Identification of KL29 type acinetobacter baumannii phage of obolenskvirus subfamily and tail-associated depolymerase activity

This study characterizes Dp49, a newly discovered bacteriophage-derived depolymerase exhibiting potent enzymatic activity against bacterial exopolysaccharides and anti-biofilm activity, which demonstrates therapeutic potential by enhancing serum-mediated bactericidal activity and anti-biofilm activity.

Jinpan Wei, Tao Yu, Qiang Wang et al. · 0 citations

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