Open access
Sep 2026
APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease.
Understanding of the genetic architecture of AD in the context of its main genetic driver is improved, and APOE-stratified insights may help understand and overcome side effects, inform clinical trial enrollment strategies, and create the scientific basis for targeted, mechanism-driven therapies in neurodegenerative di...
J. Thomassen, H. Leonard, Brittany Ulms et al.
· Nature Genetics · 0 citations