Interferon-induced OASL restricts ADAR1 p150 RNA binding and A-to-I RNA editing
The interferon (IFN)-inducible RNA editor ADAR1 p150 catalyzes adenosine-to-inosine (A-to-I) editing of host and viral double-stranded RNAs, limiting aberrant innate immune sensing and regulating gene expression. How ADAR1 p150 activity is regulated during host–virus interactions remains poorly understood. Here, we ide...
Stephanie Leon Quinonez, A. Gupta, Soowon Kang et al.
· bioRxiv · 0 citations