C. Guda

A Framework for Analyzing the Epigenetic and Transcriptomic Landscape of Cancers Using Single-Cell Multiomic Data.

Deciphering the impact of genetic variants on vulnerability to Opioid Use Disorder

Opioid Use Disorder (OUD) is a chronic condition characterized by compulsive opioid intake that drives widespread health, social, and economic burdens. To elucidate molecular contributors to addiction susceptibility, we conducted a comprehensive RNA-sequencing analysis of postmortem nucleus accumbens (NAc) t...

Integrative Proteomic Analysis Implicates Inhibition of Intracellular Protein Trafficking in Therapy-Induced Migrastasis in Prostate Cancer

KU2046-induced migrastasis appears to operate through spatial decoupling rather than structural degradation, providing a correlative framework to inhibit metastatic dissemination independent of direct cytotoxicity.

A Comprehensive Pipeline for Long Non-Coding RNA Discovery and Characterization in Cancer.

It is proposed that the upregulated lncRNA ENSG00000265613 may enhance malignancy by stabilizing the RNA target ENSG00000582008 in luminal A breast cancer, particularly given its established role in oncogenesis.