The folding of polypeptide chains into biologically active tertiary structures and the Collatz (3n+1) conjecture represent two notoriously difficult open problems characterized by extreme initial trajectory chaos collapsing into inevitable, deterministic attractors. In macromolecular biophysics, Levinthal's paradox ill...
Chou Cosmo· Zenodo (CERN European Organi...· 0 citations
The folding of polypeptide chains into biologically active tertiary structures and the Collatz (3n+1) conjecture represent two notoriously difficult open problems characterized by extreme initial trajectory chaos collapsing into inevitable, deterministic attractors. In macromolecular biophysics, Levinthal's paradox ill...
Chou Cosmo· Zenodo (CERN European Organi...· 0 citations
Modern theoretical physics, pure mathematics, and artificial intelligence have converged upon a dual epistemological crisis: while automated neural theorem engines generate sprawling, opaque derivation steps that suffer from an unbridged "epistemic justification gap" (Tanswell & Berg, M\times\Phi 2026), human mathemati...
Chou Cosmo· Zenodo (CERN European Organi...· 0 citations
Modern theoretical physics, pure mathematics, and artificial intelligence have converged upon a dual epistemological crisis: while automated neural theorem engines generate sprawling, opaque derivation steps that suffer from an unbridged "epistemic justification gap" (Tanswell & Berg, M\times\Phi 2026), human mathemati...
Chou Cosmo· Zenodo (CERN European Organi...· 0 citations
Non-convex optimization is notoriously bottlenecked by the ubiquity of high-dimensional saddle points and degenerate energy plateaus, where standard gradient descent, momentum methods, and stochastic Langevin dynamics suffer polynomial or exponential deceleration O(1/ε²) or spurious limit cycles. In this work, inspired...
Chou Cosmo· Zenodo (CERN European Organi...· 0 citations
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