Author

Christina G. Hutten

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Review Open access Sep 2026

Association of polygenic risk scores with low-density lipoprotein cholesterol levels and control: findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Background: Hypercholesterolemia is a prevalent cardiovascular (CVD) risk factor among Hispanics/Latinos; however, rates of cholesterol awareness and treatment are low in this population. Using a polygenic risk score (PRS) associated with low-density lipoprotein cholesterol (LDL) levels may help identify those who woul...

Christina G. Hutten, T. Sofer, B. Spitzer et al. · medRxiv · 0 citations

Open access Aug 2026

The role of polygenic risk in Alzheimer's disease prediction for African Americans

African Americans (AAs) face a higher risk of Alzheimer's disease and related dementias (ADRD) than European Americans (EUs), yet the utility of polygenic risk scores (PRS) in AAs remains underexplored.

Christina G. Hutten, Todd Beck, Denis A. Evans et al. · Alzheimer's & Dementia · 0 citations