African Americans (AAs) face a higher risk of Alzheimer's disease and related dementias (ADRD) than European Americans (EUs), yet the utility of polygenic risk scores (PRS) in AAs remains underexplored.
The impact of CKD transcriptional risk on AD endophenotypes is assessed by assessing the impact of CKD transcriptional risk on AD endophenotypes in individuals with chronic kidney disease.
Our goal was to determine Alzheimer's disease (AD) and related dementias (ADRD) incidence and risk factors among American Indian and Alaska Native (AI/AN) veterans, an understudied group.
Amyloid positivity does not reliably predict near‐term cognitive decline in preclinical Alzheimer's disease (AD). We tested whether digital cognitive phenotyping improves prognostic precision.
A prognostic score (PS) summarizes a patient's expected disease progression and can increase the statistical efficiency of clinical trials when included as an analysis covariate.
This Medical News article discusses research on modifiable risk factors that could protect against Alzheimer disease and other dementias.
A higher 10-year ASCVD risk was associated with faster global cognitive decline and greatest risk-linked decline occurred in the attention and delayed memory domains, suggesting AHA PREVENT may aid early identification of cognitive risk.
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