Uremic Serum Alters Gene Expression Profiles and Signaling Pathway Activity in Porcine Arterial Smooth Muscle Cells
The signaling pathways that regulate cellular redox homeostasis, the cellular waste disposal system, ER stress and autophagy are major signaling pathways involved in aSMCs’ responses to uremic serum exposure, which may contribute to the severe arterial-specific clinical symptoms observed in CKD/ESKD patients.
You-You Zheng, Kent A. Lee, U. Uriyanghai et al.
· Biomolecules · 0 citations