Author

Christopher Jin

2 papers indexed here

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Open access Aug 2026

The intrinsically disordered AR2 domain of RNase E binds mRNA translation initiation regions

Intrinsically disordered regions are widespread in RNA-processing machines. In Escherichia coli, RNase E uses its intrinsically disordered C-terminal domain (CTD) to recruit RNAs to the N-terminal catalytic domain, including mRNAs targeted by regulatory small RNAs (sRNAs), but the basis of substrate recognition and spe...

Daniel G. Mediati, Saleh Alquethamy, Christopher Jin et al. · bioRxiv · 2 citations

#gene editing Review Open access Sep 2026

RNA-guided transposases: the successors to CRISPR

CRISPR undoubtedly transformed genome editing, but it left two crucial problems unsolved. Cas nucleases cut the chromosome and leave the cell to repair the break, an error-prone process that is inefficient for installing new DNA, and Cas9 is large relative to the cargo that viral vectors can carry for gene therapy. A n...

Christopher Jin, J. Tree · Microbiology Australia · 1 citation