A universally conserved OMV-YidR conjugate nanovaccine confers broad protection against hypervirulent and carbapenem-resistant Klebsiella pneumoniae
ABSTRACT The escalating crisis of multi-drug resistant (MDR) Klebsiella pneumoniae (KP) renders standard antibiotic treatments increasingly ineffective, necessitating a shift towards alternative approaches like vaccination. However, the development of a broadly protective vaccine remains hindered by the pathogen's exte...