Post-transcriptional RNA modifications influence RNA structure and function and play
important roles in gene expression regulation and other cellular processes. Accurate identification of
RNA modification sites is therefore essential for understanding their biological functions and diseaseassociated
mechanisms. Wit...
Chun-Yan Ao, Quan Zou· Current Bioinformatics· 0 citations
Background Manganese (Mn)-induced neurotoxicity is a major public health concern. The aim of this study is to assess whether retinoic acid, a metabolite of vitamin A, can counteract manganese-induced neurotoxicity in SH-SY5Y cells by counteracting epigenetic dysregulation. Methods In vivo, we assessed neurobehavioral f...
Chun-Yan Ao, Hao Liu, Ru-Yun Ban et al.· Frontiers in Pharmacology· 0 citations
Results indicate that combining protein language models with sequence modeling and class-imbalance learning strategies is an effective way to improve peptide hormone prediction and to improve the recognition of hormone peptides as the minority class.
Chun-Yan Ao, Shihu Jiao, Xi Su et al.· Journal of Advanced Research· 0 citations
Recent progress in predicting RNA modification site-disease associations is summarized, with a focus on common modifications such as m6A, m1A, and m7G, and key challenges in this field are highlighted.
Chunyan Ao, Shihu Jiao, Xi Su et al.· Briefings in Bioinformatics· 0 citations
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