CKDu and Heat Stress Nephropathy Across Eras: Regional Heterogeneity, Occupational Evidence, and Prevention in a Warming World.
This review traces CKDu/HSN from agricultural communities to its relevance as a nephrology and public-health priority and synthesizes biomarker and histopathologic evidence supporting a tubulointerstitial phenotype and examines how climate change is expanding heat-related kidney risk.