Author

Claus O. Wilke

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

#machine learning Preprint Sep 2026

StabilityArc: Decoding Protein Sequence Embeddings into Generalizable Stability Landscapes

StabilityArc is presented, which maps frozen ESMC-600M residue representations through a shared RoPE transformer to an Lx20 matrix of substitution effects; a symmetric, contact-aware residual aids in predicting epistasis in simultaneous substitutions.

Aaron L. Feller, Andrew D. Ellington, Claus O. Wilke · 0 citations

#protein folding Open access Aug 2026

A structure-guided classification framework reveals the diversity and catalytic architecture of BECR ribonuclease

The analysis resolves an expanded BECR-fold landscape comprising canonical BECR and BECR-like superfamilies, refines the organization of canonical BECR proteins and identifies previously unrecognized families, and expands and clarify the BECR-fold landscape.

Kristi Pham, Gianlucca G. Nicastro, Audrey R. Long et al. · bioRxiv · 0 citations