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Author

Colin R. Goding

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Open access Sep 2026

Inflammatory macrophages promote metastatic potential in Triple-negative Breast Cancer through Integrated Stress Response signaling

The findings establish a macrophage-CXCL10-CXCR3-ISR signaling axis that fuels metastatic behavior in TNBC and identify this pathway as a potential node for therapeutic intervention.

Martina Crippa, Vincenzo Salemme, J. Chauhan et al. · 0 citations
Preprint Jul 2026

A quantitative model for the emergent population dynamics of the melanoma MITF rheostat

A multiscale phenotype-structured partial differential equation model for epidermal melanoma cell populations is developed, first considering subcellular MITF and then spatially uniform and spatially heterogeneous populations, highlighting that phenotype reversibility by individual cells does not imply reversibility of...

Keith L. Chambers, R. White, Colin R. Goding et al. · 1 citation

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