Author

Colm J. O'Brien

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#data science Open access Oct 2026

Barriers and Enablers to Medication Adherence & Compliance in Glaucoma – A Scoping Review Protocol

Background Glaucoma is the leading cause of irreversible blindness worldwide, with increased intraocular pressure (IOP) being the primary modifiable risk factor. It is often referred to as the “silent thief of sight” for its progressive, mostly asymptomatic disease course until advanced stages. First line treatment is...

Áine Kelly, Chriosa O’Connor, Pauline Goulding et al. · HRB Open Research · 0 citations

#protein folding Open access Oct 2026

Autotaxin induces fibrosis in lamina cribrosa cells in glaucoma

Lysophosphatidic acid (LPA) and the enzyme that generates it, autotaxin, have been shown to play a role in fibrosis in the trabecular meshwork in glaucoma, contributing to increased intraocular pressure. We wished to investigate the role of LPA and autotaxin in fibrosis of the lamina cribrosa (LC) of the optic nerve he...

Amy O’Regan, Mustapha Irnaten, Sarah Eivers et al. · Scientific Reports · 0 citations