Serotype-Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno-Associated Viral Vectors.
Adeno-associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized. This study...
Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri et al.
· Biotechnology and Bioenginee... · 0 citations