D. Barch

Reliability of computational versus noncomputational metrics of working memory and episodic memory in serious mental illness

Computational models can be used to decompose overall behavior into individual parameters that are designed to isolate specific cognitive and neural processes and provide new information about psychiatric disorders. However, it is not yet clear whether these computational parameters have sufficient reliability to repla...

Journal Pre-proof Distinct Attentional Control Profiles during Language Comprehension in Major Mental Health Disorders

Journal Pre-proof Specific, Replicable Behavioral and Neural Correlates of Sensory Over-Responsivity in Childhood

Youth Autistic Traits and Brain Activation States During Socioemotional Processing.

OBJECTIVE Different aspects of social-emotional processing are linked to unique whole-brain patterns of neural activity termed "activation states." Autistic traits in youths include impairments in socioemotional processing that vary depending on age and comorbidity. Characterizing differences in activation states assoc...

Modeling decision dynamics disentangles working memory, cognitive control and reinforcement learning and reveals clinical differences.

Various neurocognitive processes contribute to reinforcement learning (RL) and decision making, requiring careful task designs and computational modeling to disentangle them. People rely on capacity-limited working memory (WM) to rapidly and flexibly adapt behavior during learning, together with slower incremental RL p...

Intergenerational epigenetic signatures of prenatal adversity and their role in emerging child psychopathology

PSD was associated with epigenetic signatures at birth, with a subset of associations persisting across early childhood and converging on cellular stress response biology, suggesting differential biological embedding of structural versus psychological dimensions of adversity.

Functional brain network correlates of pubertal timing and depressive symptoms in preadolescence.

BACKGROUND Variation in pubertal maturation relative to same-age, same-sex peers (pubertal timing) has been linked to increased risk for depressive symptoms during adolescence. This developmental period is also characterized by substantial reorganization of functional brain networks. However, how pubertal timing relate...