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Open access

Intergenerational epigenetic signatures of prenatal adversity and their role in emerging child psychopathology

Anna M. Constantino-Pettit A. Lussier Mia Ruppel Erin C. Dunn D. Czamara T. Smyser Ryan Bogdan B. Warner C. Smyser D. Barch C. Rogers J. Luby
Jul 2026 · bioRxiv · 0 citations · 60 references
Biology

TL;DR

PSD was associated with epigenetic signatures at birth, with a subset of associations persisting across early childhood and converging on cellular stress response biology, suggesting differential biological embedding of structural versus psychological dimensions of adversity.

DOI Semantic Scholar
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