5-Fluorouracil (5-FU) is a widely used chemotherapeutic agent for the treatment of various solid malignancies; however, its clinical application is also associated with hepatotoxicity. As the liver is the primary site of 5-FU metabolism, excessive accumulation of the drug and its metabolites can lead to hepatic injury...
Sharmila Muthusethupathi, D. Ezhilarasan· Drug metabolism reviews (Sof...· 0 citations
This commentary highlights the growing burden of lean MASLD, the importance of visceral adiposity and cardiometabolic dysfunction, and population-specific genetic influences in Indian populations.
Karthik Shree Harini, D. Ezhilarasan· npj Metabolic Health and Dis...· 0 citations
The biosynthesized AgNPs exhibited potent antibacterial activity against multidrug-resistant wound pathogens by disrupting bacterial membrane integrity, along with significant antioxidant and antidiabetic properties.
R. Snega, Aruchamy Mohanprasanth, Jeyasingh Immanuel Suresh et al.· Microbial Pathogenesis· 0 citations
The findings of the present study suggest that CDNG-1 attenuates alcohol-induced chronic liver injury and may represent a potential therapeutic candidate for ALD.
Karthik Shree Harini, D. Ezhilarasan, Munusamy Karthick· Toxicology and Applied Pharm...· 0 citations
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