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D. R. Siemens

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Review Open access Sep 2026

Comparison of Gene Enrichment Between Prostate Tissue and Urine for Non-Invasive Biomarker Development.

BACKGROUND For prostate cancer (PCa), early diagnosis and biomarker-based patient stratification can improve clinical decision-making and post-treatment prognosis. PCa biomarkers are best validated in tissue following comprehensive histopathologic review; however, urinary biomarkers can be obtained non-invasively and a...

Yuan-Dong Xing, Min-Qi Xu, Di-On Dan et al. · 0 citations
Open access Aug 2026

Hypoxia and epithelial to mesenchymal transition pathways are enriched in bladder tumor epithelium adjacent to tertiary lymphoid structures

Findings indicate that a pro-tumorigenic microenvironment associated with disease progression in bladder cancer exists within peri-tumoral TLS and potentially a factor underlying contrasting therapeutic associations potentially driven by live microbial versus targeted immunomodulatory therapy in NMIBC and MIBC.

Kartik Sachdeva, Priyanka Yolmo, Abdulhameed Abdulhamed et al. · 0 citations

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