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Sep 2026

A neutralizing epitope within the VP1 protein of duck hepatitis A virus type 3: From single-cell BCR discovery to in vivo protection.

Duck hepatitis A virus type 3 (DHAV-3) continues to circulate, threatening the health of duck flocks and highlighting the urgent need for novel antibody-based interventions. In this study, we systematically profiled the DHAV-3-specific B cell immune repertoire in VP1-immunized mice, using high-throughput single-cell RN...

Sai-Sai Zhao, Fang-Bo Wu, Rui-Qi Shi et al. · 0 citations
Sep 2026

LwaCas13a protein- and crRNA-enabled RPA-CRISPR/Cas13a platform for rapid visual differentiation of goose parvovirus and novel goose parvovirus.

Waterfowl parvoviruses, including goose parvovirus and novel goose parvovirus, are highly transmissible pathogens that pose serious threats to flock health and the poultry industry. In this paper, we report a macromolecule-enabled recombinase polymerase amplification (RPA)-CRISPR/Cas13a platform for the rapid, sensitiv...

Shu-Min Yu, Zhen Chen, Jia-Hao Zhang et al. · 0 citations

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