Author

Da-Qing Wang

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Open access Aug 2026

Prognostic nutritional index in evaluating the prognosis of ICIs in patients with advanced esophageal squamous carcinoma

Objective This study aimed to investigate the association between the Prognostic Nutritional Index (PNI) and the prognosis of advanced esophageal squamous cell carcinoma (ESCC) patients treated with immune checkpoint inhibitors (ICIs). Methods We retrospectively analyzed the clinical data of 157 advanced ESCC patients...

Q. Shi, Man Li, Da-Qing Wang et al. · Frontiers in Oncology · 0 citations

Review Open access Sep 2026

Toward trustworthy virtual cells: a roadmap for perturbation-resolved, context-aware, and experimentally validated cell models

Single-cell perturbation technologies, multimodal omics, spatial profiling, and generative modeling are transforming the virtual cell from a theoretical concept into a practical objective for cell biology. Yet current efforts often emphasize model scale, data volume, or predictive breadth, while the trustworthiness req...

Wang-Shu Li, Aziz ur Rehman Aziz, Bo-Wen Xu et al. · Frontiers in Cell and Develo... · 0 citations

Review Open access Sep 2026

Circulating and tumor-infiltrating immune cell profiles in cervical cancer checkpoint blockade: multi-omics biomarkers of response and resistance

A blood-to-tumor framework is proposed in which dynamic peripheral phenotypes may monitor systemic immune competence, while tissue multi-omics may identify local immune exclusion, terminal exhaustion, and myeloid suppression.

Wang-Shu Li, Xiao-Hui Yu, Wen-Juan Wei et al. · Frontiers in Immunology · 0 citations