Open access
Sep 2026
Structural basis of interaction between Pol1 and DnaN from Mycobacterium tuberculosis
The interaction between PolI with the β-clamp, mediated by a CBM unique to the Mycobacteriales order, highlights the mechanistic distinctiveness of genome replication in Mtb and phylogenetically related organisms, and has important implications for drug discovery.
Dalchand Sharma, Deepak T. Nair
· bioRxiv · 0 citations