Author

Dan-Dan Song

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Review Open access Sep 2026

Effects of higher versus lower protein intake in critically ill patients: a systematic review and meta-analysis

Background The optimal protein dose for critically ill patients remains uncertain, and emerging evidence suggests that the effects of higher protein intake may differ across clinically relevant subgroups. Methods PubMed, Embase, Web of Science, Scopus, and the Cochrane Library were searched for randomized controlled tr...

Shi-Ge Li, Yu-Sheng Hou, Xin-Yu Li et al. · Frontiers in Nutrition · 0 citations

Aug 2026

A targetable ALDH3A2-NRF2 axis mediates KEAP1-mutant tumour development via ferroptosis inhibition.

A novel NRF2 regulatory pathway is revealed and ALDH3A2 is suggested as a promising druggable target for KEAP1-mutant tumours by performing an aldehyde dehydrogenase 3 family shRNA screen.

Li Yang, Xiao Zhuang, Jing Han et al. · Cell Death and Differentiati... · 0 citations

Review Open access Aug 2026

Mitochondrial ecosystem restoration in Alzheimer’s disease: from mechanisms to multi-target therapeutic strategies

This study synthesizes the latest advances in mitochondrial-targeted therapies, framing them within a “Mitochondrial Ecological Restoration” perspective, and analyzes the molecular mechanisms by which mitochondrial-targeted therapies modulate oxidative stress, mitochondrial dynamics, mitophagy and neuroinflammation.

Dan-Dan Song · Frontiers in Cell and Develo... · 0 citations