2026
The Open Conformation of CCT: How to Achieve High Resolution Using CryoEM.
Jorge Gutiérrez-Seijo, César Santiago, Sergio Pipaón et al.
· Methods in molecular biology · 0 citations
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2026
CryoEM Strategies for Elucidating the Closed State Architecture of CCT.
This study investigates the eukaryotic chaperonin CCT, a ~1 MDa hetero-oligomeric complex essential for the folding of key substrates such as actin, tubulin, and WD40 family members and demonstrates that subunit assignment and atomic modeling are achievable by exploiting subunit-intrinsic structural features alone.
Jorge Gutiérrez-Seijo, Ana Cuervo, Sergio Pipaón et al.
· Methods in molecular biology · 0 citations