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PARTIAL ALTERNATIVE SPLICING IN CARRIERS OF DPYD rs75017182 EXPLAINS A MODEST ASSOCIATION WITH SEVERE
It is demonstrated that rs75017182‐ C promotes alternative splicing in the minigene plasmid model, and that the level of splicing may be affected by additional variants in linkage disequilibrium with rs75017182.
Emerging target antigen landscape for CAR T-cell therapy in solid tumors: current advances and future directions
A conceptual framework for rational target selection and combinatorial design is provided for rational target selection and combinatorial design of next-generation CAR T-cell therapies with improved precision and durability against solid tumors.