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Author

Deepanshi Saxena

2 papers indexed here

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Review Aug 2026

Outer membrane as a drug target for the treatment of GNB infections.

Antimicrobial resistance among Gram-negative bacteria poses a critical challenge to global public health. A key factor contributing to this resistance is their unique outer membrane (OM), which serves as a formidable barrier to many antibiotics, particularly hydrophobic and high-molecular-weight compounds. The OM not o...

Urjoshi Chattoraj, Ayesha Fatima, Deepanshi Saxena et al. · 0 citations
#protein folding Open access Sep 2026

A Small Molecule Substrate Mimic to Inhibit Bacterial Hsp70 Chaperone Function.

Given the rapid spread of antibiotic resistance worldwide, it is imperative to develop new strategies against pathogenic bacteria. Here, we report a small-molecule inhibitor of bacterial heat shock protein 70 (Hsp70), called DnaK, a central component of the bacterial protein chaperone network. Screening of an in-house...

Tulsi Upadhyay, Reshma Kumari, Yogesh M. Gangarde et al. · 0 citations

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