Review Article: Beyond the Therapeutic Ceiling in Inflammatory Bowel Disease-Mechanism-Based Positioning and Emerging Therapeutic Strategies.
BACKGROUND Therapeutic options for inflammatory bowel disease (IBD) have expanded rapidly with the introduction of selective interleukin (IL)-23 inhibitors, Janus kinase inhibitors, sphingosine-1-phosphate receptor modulators, and several emerging therapeutic classes. Consequently, the major clinical challenge has shif...