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Open access Nov 2024

MolReFlect: Toward In-Context Fine-Grained Alignments Between Molecules and Texts

MolReFlect is proposed, a novel teacher-student framework, where a teacher LLM first generates and refines mappings between caption phrases and SMILES substructures and then explicitly teaches these detailed alignments to a student LLM, enabling LLMs to significantly outperform previous baselines.

Jiatong Li, Yunqing Liu, Wei Liu et al. · 13 citations
Book Open access Aug 2026

Chem-R: Learning to Reason as a Chemist

The proposed Chem-R, a general Chemical Reasoning model designed to emulate the deliberative processes of chemists, achieves state-of-the-art performance on comprehensive benchmarks, surpassing leading LLMs, including Gemini-3-Pro and Kimi-k2.5.

Weida Wang, Benteng Chen, Di Zhang et al. · 0 citations