The fibrocystin C-terminal domain inhibits Src/STAT3 signal induced cystogenesis of kidney epithelial cells.
FPCct appears to act like a physiological suppressor of cystogenic signaling, as found in healthy kidney epithelia, that is essential for maintaining epithelial homeostasis.
F. Hassan, Susanne T. Hahnenstein, A. Kraus et al.
· American Journal of Physiolo... · 0 citations