Nano-Oncology Targeting the Lactate-MCT1/MCT4-Histone Lactylation Axis: A New Hallmark-Based Strategy Against Metastatic Cancer Progression
Metastatic progression remains the principal cause of cancer-related mortality because disseminating tumor cells acquire interlocking metabolic, epigenetic, stromal and immune-adaptive programs that are insufficiently controlled by conventional cytotoxic and single-target molecular therapies. Among these programs, lact...