Validation and analysis of 12,000 AI-driven CAR-T designs in the Bits to Binders competition.
Artificial intelligence (AI) methods for proteins have advanced rapidly, improving structure prediction and design, particularly for de novo binders. However, most evaluations emphasize binding affinity rather than higher-order biological function. We present Bits to Binders, a global competition evaluating de novo bin...
Clayton W. Kosonocky, Alex M. Abel, Aaron L. Feller et al.
· Molecular Systems Biology · 6 citations
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