CHROMATIN SEQUENCING Single-molecule regulatory architectures captured by chromatin fiber sequencing
Fiber-seq exposed widespread plasticity in the linear organization of individual chromatin fibers and illuminated principles guiding regulatory DNA actuation, the coordinated actuation of neighboring regulatory elements, single-molecule nucleosome positioning, and single-molecule transcription factor occupancy.
Andrew B. Stergachis, Brian M. Debo, E. Haugen et al.
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