E. J. Foster

The AP-1 adaptor complex is required for cell surface modifications and the survival of Cryptococcus neoformans in phagocytic cells

ABSTRACT The pathogenic yeast Cryptococcus neoformans causes life-threatening meningoencephalitis in individuals with compromised immune systems. The ability of the fungus to cause disease depends on key cell-surface features, such as a polysaccharide capsule that protects it from the mammalian immune system. However,...