E. Luo

Accuracy of Guide-Free, Mixed Reality-Assisted Patient Specific Implant Fixation for Maxillary Repositioning: A Cohort Study.

OBJECTIVE To develop a mixed reality (MR)-assisted, guide-free workflow for patient-specific implant (PSI)-based maxillary fixation and evaluate its positioning equivalence and procedural efficiency relative to conventional guide-assisted PSI fixation. METHODS In this non-randomized cohort study, 28 patients undergoi...

Craniomaxillofacial Peripheral Osteomas in Gardner Syndrome.

Gardner syndrome is a precancerous condition featuring familial adenomatous polyposis (FAP), multiple osteomas, and soft tissue tumors. Craniomaxillofacial peripheral osteomas often cause visible facial deformities, enabling early detection of the syndrome-frequently before FAP manifests-thus providing a critical windo...

SIRT1 promotes endothelial activity and osteogenesis in vitro and ameliorates age-related skeletal regeneration defects in vivo.

Understanding age-driven bone weakening mechanisms is essential for developing precision therapeutic strategies. This study systematically investigated skeletal aging, focusing on the critical decline of SIRT1 and its impact on type H vessels and osteogenic cells. We found that SIRT1 markedly enhanced both endothelial...

Mechanosignaling Promotes Osteogenic-Angiogenic Coupling in Bone Tissue