Author

E. Munson

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Open access Aug 2026

Investigating the impact of trehalose crystallization on protein aggregation in lyophilized formulations

Trehalose is a commonly used lyoprotectant for stabilizing proteins in lyophilized formulations. Its physical state plays a critical role in maintaining both the physical and chemical stability of proteins. In this study, three types of protein/trehalose systems were studied to understand the impact of trehalose crysta...

Rachana Sapkota, Isabella Perez Mejia, Cole W. Tower et al. · AAPS Open · 0 citations

#protein folding Aug 2026

Impact of hydrolyzed gelatin and hydroxypropyl-β-cyclodextrin as polymeric excipients on physical stability and injectability of high-concentration protein suspensions.

The current work highlighted the potential of polymer-based excipient systems for developing high-concentration injectable suspensions of proteins and their combinations on the viscosity, injectability, and stability.

Chanakya D. Patil, Yi-Jing Huang, K. Arte et al. · International journal of pha... · 0 citations