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E. Topakas

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#protein folding Open access Sep 2026

Rational mutagenesis reveals substrate-specific activity shifts in the Antarctic polyesterase MoPE.

Overall, this work demonstrates that rational mutagenesis can alter polyesterase activity against structurally distinct biodegradable polyesters, providing potential mechanistic insights to guide the development of specialized biocatalysts for targeted polyester degradation.

Konstantinos Makryniotis, Panagiota Karampa, M. Dimarogona et al. · 0 citations
Open access Aug 2026

Biocatalytic Production of Oxidized Furan Derivatives from Lignocellulosic Sugar-Rich Streams Using a Novel Fungal Glyoxal Oxidase

This study focused on the recombinant production and characterization of a GlyOx from the medicinal basidiomycete Ganoderma lucidum capable of oxidizing HMF and FA, marking the first time such enzymatic activity has been demonstrated on furans originating from genuine lignocellulosic biomass sugar streams.

Maria-Konstantina Karonidi, Κoar Chorozian, A. Marianou et al. · 1 citation

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