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Eugenio Piasini

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Open access Sep 2026

Prion Protein Deficiency Results in Synaptic, Neural Network and Behavioral Alterations

The cellular form of the prion protein (PrPC) is known for its involvement in the pathogenesis of prion diseases. Recent research implicates the physiological isoform of PrP in neuronal development, excitability, and synaptic plasticity, as well as in other biological processes. However, its precise function in the dev...

Anna Burato, Alessio Di Clemente, Camilla Lodetti et al. · 1 citation

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