Author

F. Dormont

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Open access Sep 2026

Causal Inference and Pathway Embeddings with Real-World Data for Enhanced Trial Design Across Diseases

Randomized controlled trials (RCTs) are often considered the gold standard for causal inference, but their implementation can be costly, time-consuming, and sometimes infeasible due to ethical or practical constraints. The so-called target trial emulation framework introduced the systematic use of observational data fo...

Margot Blanchon, Carrie Heller, Maksim Kriukov et al. · Mathematical and Computation... · 1 citation

Preprint Aug 2026

Explainable Transformer Models for Clinical Prediction Tasks on Structured Electronic Health Records

BERT-LER is presented, a BERT-style model for coded EHR timelines pretrained and fine-tuned from a de-identified EHR dataset of 75 million patients, that encodes laboratory test results as discrete tokens while retaining graded information through percentile-based binning, paired with Integrated Gradients for token-lev...

Jun-Ni Du, Lukas Adamek, Maxim A Kryukov et al. · 0 citations