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Author

F. Heinzl

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Open access Sep 2026

Fetal Brain Abnormalities in Trisomy 21 and Associated Neurodevelopmental Outcome: Key Factors to Identify Differences in Neurodevelopmental Outcome?

Trisomy 21 (T21) is associated with various neurological impairments. However, the mechanisms of fetal brain development in T21 and their impact on neurodevelopmental outcomes remain unclear, limiting prenatal counseling. Therefore, this study aims to assess neuropathological changes in fetuses with T21 and the associa...

C. Haberl, P. Palmrich, Eva Karner et al. · 0 citations
Open access Sep 2026

Pathologic complete response and survival according to germline BRCA1/2 status in triple-negative breast cancer.

BACKGROUND Germline BRCA1/2 pathogenic variants (gBRCA-PV) are associated with chemosensitivity in triple-negative breast cancer (TNBC), but whether higher pathologic complete response (pCR) rates translate into improved long-term outcomes remains uncertain. We assessed associations of gBRCA-PV status with pCR, recurre...

Paulina Gebhart, F. Heinzl, Chiara Kahl et al. · 0 citations

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