Author

F. Hohendanner

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Open access Sep 2026

Cluster-Based Phenotyping in an HFpEF Population Identifies a Biomarker-High, Atrial-Dysfunction Phenotype with Impaired Quality of Life, Reduced Exercise Capacity and Higher Healthcare Utilization

Background/Objectives: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome. Atrial remodeling represents an important dimension of HFpEF beyond the presence of atrial fibrillation (AF). We aimed to identify clinically meaningful atrial phenotypes using unsupervised clustering. Methods: Ov...

S. Haack, Frank Edelmann, F. Spinka et al. · Journal of Clinical Medicine · 0 citations

Open access Jul 2026

Development of an LLM pipeline exceeding physician-documented cardiovascular risk scores under routine clinical conditions

P Pipelines combining expert-curated knowledge injection, LLM-based clinical data extraction, and deterministic score calculation enable accurate and scalable cardiovascular risk score computation from unstructured real-world clinical data, outperforming physician-documented scores.

T. Roeschl, Marie Hoffmann, A. Unbehaun et al. · European Heart Journal - Dig... · 0 citations

Open access Aug 2026

Mortality reduction with implanted defibrillator for primary prevention of sudden death after Myocardial Infarction: temporal trends in the PROFID study.

In this analysis including a large cohort of post-myocardial infarction patients with reduced LVEF, the estimated mortality reduction associated with primary prevention ICD implantation progressively decreased over time.

Alireza Sepehri Shamloo, T. Chiba, J. G. Tijssen et al. · European Heart Journal · 0 citations