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Metabolic syndrome (MetS) is a major global health challenge associated with increased risks of cardiovascular disease, type 2 diabetes, and mortality, particularly among older adults. B vitamins are essential cofactors in the homocysteine–methionine, folate, and tryptophan–kynurenine pathways, which regulate inflamm...
The definite clinical significance of APC mutations in PTC emergence is not fully understood, and additional prospective and translational studies are required to elucidate their biological and clinical advantages in diagnosis, prognosis, targeted therapy, and individualized patient management.
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