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Author

F. Thol

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Case report Open access Sep 2026

Teclistamab in relapsed, multi-refractory acquired hemophilia A after failure of anti-CD19 CAR-T cell therapy.

A patient with relapsed acquired hemophilia A (AHA), who previously failed multiple lines of immunosuppressive therapy (IST) including autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy received teclistamab, a bispecific monoclonal antibody engaging autologous CD3-positive T cells with the B cell matur...

C. Dobbelstein, Kalin Stoyanov, Krasimira Aleksandrova et al. · 0 citations
Open access Sep 2026

DDX41 mutations establish a separate entity in acute myeloid leukemia with distinct survival outcomes

Recurrent germline variants in DDX41 represent the most common inherited predisposition to adult myeloid neoplasms, occurring in approximately 3% – 5% of patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). 1,2 Clinically, patients with DDX41 ‐ mutated AML are typically older at diagnosis, pred...

Carolin Seeling, Maral Saadati, D. Späth et al. · 0 citations

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